2-Pyrrolidone

2-Pyrrolidone

SCHEMBL28375404

O=C1CCCN1.[Na+].[OH-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of 2-Pyrrolidone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL27877554 0.94
2-Pyrrolidone SCHEMBL27610056 0.94
2-Pyrrolidone SCHEMBL9304498 0.94 OR51E2 (1.00)
2-Pyrrolidone SCHEMBL27827832 0.94
2-Pyrrolidone SCHEMBL4299593 0.94
2-Pyrrolidone SCHEMBL2167448 0.94 OR51E2 (1.00)
2-Pyrrolidone SCHEMBL2389 0.94
2-Pyrrolidone SCHEMBL3453306 0.91
2-Pyrrolidone SCHEMBL2518866 0.91
2-Pyrrolidone SCHEMBL5274639 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109548727-B Deepwater net cage with pulley lifting mechanism 浙江海洋大学 2021-08-24 CN claimed
CN-113143828-A Repair type facial mask essence free of antiseptic components and preparation method thereof 浙江自贸区仟草生物科技有限公司 2021-07-23 CN claimed
CN-112391433-A Human cell polypeptide extraction and application method 山东发现生物技术有限公司 2021-02-23 CN claimed
CN-110951339-A Cement-based floor polymer waterproof coating, preparation method and equipment 广东汉耐斯新材料科技有限公司 2020-04-03 CN claimed
CN-109548727-B Deepwater net cage with pulley lifting mechanism 浙江海洋大学 2021-08-24 CN disclosed
CN-113143828-A Repair type facial mask essence free of antiseptic components and preparation method thereof 浙江自贸区仟草生物科技有限公司 2021-07-23 CN disclosed
CN-112391433-A Human cell polypeptide extraction and application method 山东发现生物技术有限公司 2021-02-23 CN disclosed
CN-211159479-U Preparation equipment of cement-based base plate polymer waterproof coating 广东汉耐斯新材料科技有限公司 2020-08-04 CN disclosed
CN-110951339-A Cement-based floor polymer waterproof coating, preparation method and equipment 广东汉耐斯新材料科技有限公司 2020-04-03 CN disclosed
CN-106164138-B Polyphenylene sulfide block copolymer and its manufacturing method 东丽株式会社 2019-04-05 CN disclosed