SCHEMBL802630

SCHEMBL802630

C=C(C)C(=O)Oc1ccc2c(c1)COc1cc(OC(=O)C(=C)C)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.48
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KMT2A Q03164 5/20 0.43
MEN1 O00255 2/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2C9 P11712 1/20 0.41
ATM Q13315 1/20 0.41
ELANE P08246 1/20 0.40
AAK1 Q2M2I8 2/20 0.40
ROCK2 O75116 4/20 0.40
PIK3CA P42336 4/20 0.39
PIK3CD O00329 3/20 0.39
PIK3CG P48736 3/20 0.39
PIK3CB P42338 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15292004 0.92 MAPT (0.44) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL803071 0.87 AKR1B1 (0.43) MAPTALDH1A1SMN1; SMN2AAK1ROCK2
SCHEMBL75194 0.85 MAPT (0.49) MAPTALDH1A1SMN1; SMN2KMT2AHSD17B10
SCHEMBL18365493 0.85 MAPT (0.60) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL783519 0.81 KMT2A (0.51) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL2604680 0.81 KMT2A (0.48) MAPTALDH1A1SMN1; SMN2KMT2AHSD17B10
SCHEMBL29853545 0.78 MAPT (0.71) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL74957 0.77 MAPT (0.52) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL29329864 0.76 ALDH1A1 (0.48) MAPTALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL29329861 0.76 ACHE (0.49) MAPTALDH1A1SMN1; SMN2ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
EP-2432851-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120069289-A1 LIQUID CRYSTAL DISPLAY LPXN, VCL, ACP3 MAPT 38/4885ALDH1A1 3543/4885SMN1; SMN2 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.