Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | RXRG | P48443 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617487 | 0.73 | ELANE (0.46) | MEN1KMT2AALDH1A1LMNARECQL | |
| SCHEMBL8028404 | 0.72 | RXRA (0.38) | ALDH1A1RXRARXRBRXRGRARA | |
| SCHEMBL16301295 | 0.70 | RAB9A (0.34) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24359494 | 0.69 | EGFR (0.39) | RXRARXRBRXRGRARACYP1A2 | |
| Lithium SCHEMBL29601477 | 0.69 | EGFR (0.38) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL23143159 | 0.68 | RXRA (0.50) | RXRARXRBRXRGRARACYP3A4 | |
| SCHEMBL26081392 | 0.68 | RXRA (0.37) | ALDH1A1RXRARXRBRXRGRARA | |
| SCHEMBL12020468 | 0.67 | BTN3A1 (0.36) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL8028400 | 0.67 | CYP1A2 (0.35) | ALDH1A1RXRARXRBRXRGRARA | |
| SCHEMBL22320162 | 0.67 | RXRA (0.36) | ALDH1A1RXRARXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653431-B1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-01 | — | — | EP | disclosed |
| US-5498797-A | Bis(phosphinozlkoxy)biaryl compounds and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0653431-A1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |