Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.38 |
| ▸ | RXRB | P28702 | 5/20 | 0.38 |
| ▸ | RXRG | P48443 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525106 | 0.75 | CYP1A2 (0.37) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL24359494 | 0.74 | EGFR (0.39) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL3417517 | 0.73 | CYP2C19 (0.42) | RXRACYP1A2CYP3A4CYP2C9TSHR | |
| Lithium SCHEMBL29601477 | 0.73 | EGFR (0.38) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL8026520 | 0.72 | MEN1 (0.47) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL26081392 | 0.72 | RXRA (0.37) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL22320162 | 0.71 | RXRA (0.36) | RXRARXRBRXRGRARACYP1A2 | |
| SCHEMBL23143159 | 0.70 | RXRA (0.50) | RXRARXRBRXRGRARACYP3A4 | |
| SCHEMBL11488213 | 0.70 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL4154409 | 0.70 | TSHR (0.39) | RXRACYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653431-B1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-01 | — | — | EP | disclosed |
| US-5498797-A | Bis(phosphinozlkoxy)biaryl compounds and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0653431-A1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |