Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377472 | 0.89 | ACLY (0.38) | ACLYACACAHSD11B1PTPN11PTGS1 | |
| SCHEMBL159792 | 0.85 | EBP (0.47) | ACLYACACAHSD11B1PTPN11EBP | |
| SCHEMBL464758 | 0.85 | HSD11B1 (0.49) | ACLYACACAHSD11B1PTPN11PTGS1 | |
| SCHEMBL6341662 | 0.81 | HSD11B1 (0.45) | ACLYACACAHSD11B1PTGS1PTGS2 | |
| SCHEMBL6410134 | 0.78 | GABRA1 (0.58) | TSHRTDP1F2POLBDPP4 | |
| Niacin SCHEMBL6684757 | 0.75 | EBP (0.39) | ACLYACACAHSD11B1PTPN11PTGS1 | |
| SCHEMBL10635071 | 0.74 | HSD11B1 (0.40) | ACLYACACAHSD11B1PTPN11PTGS1 | |
| Ferulate SCHEMBL2563897 | 0.71 | MEN1 (0.42) | ACLYACACAHSD11B1TSHRTDP1 | |
| SCHEMBL2257958 | 0.70 | EBP (0.45) | ACLYACACAHSD11B1EBP | |
| SCHEMBL10638570 | 0.69 | EBP (0.40) | ACLYACACAHSD11B1PTPN11EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000056269-A2 | NATURAL PREPARATION FOR TREATMENT OF MALE PATTERN HAIR LOSS | CHIZICK STEVEN (CA) | 2000-09-28 | — | — | WO | disclosed |