Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007701 | 0.92 | CTRC (0.41) | CTRCNAMPTPOLBCYP1A2MAPT | |
| SCHEMBL8036259 | 0.87 | NR1H4 (0.39) | CTRCNAMPTPOLBCYP1A2MAPT | |
| SCHEMBL8032185 | 0.87 | LMNA (0.45) | POLBCYP1A2MAPTADORA3KDM4E | |
| SCHEMBL8021759 | 0.85 | KDM4E (0.49) | DHODHCTRCPOLBCYP1A2DHPS | |
| SCHEMBL8032814 | 0.85 | NAMPT (0.39) | CTRCNAMPTPOLBCYP1A2MAPT | |
| SCHEMBL4008885 | 0.82 | FABP3 (0.41) | DHODHCTRCPOLBCYP1A2DHPS | |
| SCHEMBL4009406 | 0.81 | FABP4 (0.42) | DHODHCTRCNAMPTPOLBCYP1A2 | |
| SCHEMBL4010263 | 0.79 | DHPS (0.41) | NAMPTPOLBCYP1A2DHPSMAPT | |
| SCHEMBL8024898 | 0.78 | MAPT (0.40) | NAMPTPOLBCYP1A2MAPTALDH1A1 | |
| SCHEMBL8027574 | 0.77 | NAMPT (0.39) | NAMPTDHPSMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |