Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014827 | 0.87 | NAMPT (0.37) | DHPSCYP1A2POLBRAB9AALOX5 | |
| SCHEMBL4014170 | 0.84 | MAPT (0.43) | DHPSCYP1A2POLBRAB9AMAPT | |
| SCHEMBL8032185 | 0.83 | LMNA (0.45) | CYP1A2POLBRAB9AMAPTLMNA | |
| SCHEMBL4007708 | 0.82 | CYP1A2 (0.40) | DHPSCYP1A2POLBRAB9AMAPT | |
| SCHEMBL4011727 | 0.79 | RAB9A (0.41) | CYP1A2RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL8027468 | 0.79 | DHODH (0.41) | DHPSCYP1A2POLBRAB9AMAPT | |
| SCHEMBL4011709 | 0.78 | MAPT (0.41) | DHPSCYP1A2POLBRAB9AMAPT | |
| SCHEMBL8038397 | 0.74 | TARBP2 (0.49) | CYP1A2POLBRAB9AALOX5MAPT | |
| SCHEMBL8021662 | 0.74 | KDM4E (0.50) | CYP1A2POLBRAB9AMAPTALDH1A1 | |
| SCHEMBL4010739 | 0.74 | SIRT2 (0.45) | RAB9AALOX5MAPTLMNATARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |