Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4069025 | 1.00 | PKM (0.47) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL8854354 | 0.77 | PKM (0.44) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL8522617 | 0.77 | OR51E2 (0.33) | — | |
| Acetic Acid SCHEMBL720227 | 0.74 | PKM (0.41) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL1949358 | 0.73 | PKM (0.40) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL17005444 | 0.73 | PKM (0.40) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL3804389 | 0.73 | PKM (0.40) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL1627225 | 0.72 | PKM (0.52) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL2874562 | 0.72 | PKM (0.52) | PKMKDM4ETHRBHTTALDH1A1 | |
| Acetic Acid SCHEMBL9778642 | 0.72 | PKM (0.52) | PKMKDM4ETHRBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283938-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA NV (BE) | 2021-09-16 | — | — | US | disclosed |
| CN-110546567-A | Lithographic printing plate precursor | AGFA NV | 2019-12-06 | — | — | CN | disclosed |
| WO-2018192932-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA NV (BE) | 2018-10-25 | — | — | WO | disclosed |
| EP-3392709-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA NV (BE) | 2018-10-24 | — | — | EP | disclosed |
| EP-0696287-B1 | UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN SPA (IT) | 2000-03-08 | — | — | EP | disclosed |
| US-5700788-A | Ureido derivatives of naphthalenephosphonic acids | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283938-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | LOXL1, LOXL2, LOXL3 | PKM 3851/4885KDM4E 2807/4885THRB 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.