Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4069025 | 0.77 | PKM (0.47) | — | |
| Acetic Acid SCHEMBL8027581 | 0.77 | PKM (0.47) | — | |
| Butyric Acid SCHEMBL4942354 | 0.75 | FFAR3 (0.45) | OR51E2FFAR3 | |
| Glycerin SCHEMBL8151443 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL1685689 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL15061 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL1685690 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL33458 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL1685695 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN | |
| Glycerin SCHEMBL203757 | 0.72 | LMNA (0.60) | OR51E2FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |