Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041202 | 0.90 | CTSV (0.52) | ALDH1A1KDM4EGAATDP1HPGD | |
| SCHEMBL10340241 | 0.87 | GAA (0.59) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL8039699 | 0.86 | TSHR (0.58) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL8037914 | 0.78 | PDE5A (0.54) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL8037877 | 0.78 | TSHR (0.59) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL8027785 | 0.77 | MRGPRX4 (0.48) | KDM4ETSHRTDP1SMN1; SMN2KMT2A | |
| SCHEMBL8041262 | 0.77 | TSHR (0.64) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL978857 | 0.77 | HTT (0.64) | ALDH1A1GAANPC1SMN1; SMN2BRD4 | |
| SCHEMBL8037867 | 0.76 | TSHR (0.57) | ALDH1A1KDM4EGAATSHRTDP1 | |
| SCHEMBL8039720 | 0.76 | TSHR (0.67) | ALDH1A1KDM4EGAATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |