Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.44 |
| ▸ | MMP3 | P08254 | 10/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410121 | 0.90 | MMP2 (0.47) | MMP2MMP3MMP1POLB | |
| SCHEMBL7370348 | 0.80 | MMP2 (0.46) | MMP2MMP3MMP1 | |
| SCHEMBL7371393 | 0.79 | RAB9A (0.43) | MMP2MMP3ADAM17 | |
| SCHEMBL7411915 | 0.75 | MMP2 (0.49) | MMP2MMP3MMP1POLB | |
| SCHEMBL8197269 | 0.74 | MMP1 (0.42) | MMP2MMP3MMP1TNFADAM17 | |
| SCHEMBL8197822 | 0.74 | MMP1 (0.42) | MMP2MMP3MMP1TNFADAM17 | |
| SCHEMBL8028148 | 0.74 | MMP1 (0.52) | MMP2MMP3MMP1POLB | |
| SCHEMBL7513209 | 0.74 | MMP1 (0.44) | MMP2MMP3MMP1TNFADAM17 | |
| SCHEMBL7401014 | 0.72 | MMP2 (0.47) | MMP2MMP3MMP1TNFADAM17 | |
| SCHEMBL8026129 | 0.72 | MMP3 (0.40) | MMP2MMP3MMP1TNFADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | claimed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | claimed |
| US-5919940-A | TERT-LEUCINE-THIAZOL-2-YLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5859253-A | L-TERT-LEUCINE-2-PYRIDYLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | disclosed |
| US-5747514-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |