Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14232084 | 0.70 | THRB (0.40) | ALDH1A1MAPK1PDE4BMAPTTDP1 | |
| SCHEMBL9577638 | 0.69 | KMT2A (0.42) | ALDH1A1MAPK1LMNAGAATSHR | |
| SCHEMBL9298160 | 0.67 | NOTUM (0.41) | FPR2NOTUMALDH1A1PDE4BTYMS | |
| SCHEMBL6597024 | 0.67 | PGR (0.39) | ALDH1A1MAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL16339743 | 0.67 | PTGS2 (0.42) | ALDH1A1MAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL29581434 | 0.66 | PGR (0.51) | FPR2NOTUMTYMSKMT2APGR | |
| SCHEMBL27315440 | 0.66 | ALDH1A1 (0.47) | NOTUMALDH1A1TYMSKMT2ANPSR1 | |
| SCHEMBL182096 | 0.66 | PGR (0.51) | FPR2NOTUMTYMSKMT2APGR | |
| SCHEMBL12275268 | 0.66 | TYMS (0.40) | FPR2NOTUMALDH1A1MAPK1TYMS | |
| SCHEMBL15679182 | 0.64 | MAPK1 (0.41) | ALDH1A1MAPK1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |