Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198750 | 1.00 | ELANE (0.53) | ELANEPRTN3ATMALDH1A1CTSK | |
| SCHEMBL7202814 | 1.00 | ELANE (0.53) | ELANEPRTN3ATMALDH1A1CTSK | |
| SCHEMBL12906609 | 0.85 | ATM (0.61) | ELANEPRTN3ATMCTSKCTSS | |
| SCHEMBL7763449 | 0.82 | TRPM8 (0.58) | ATMALDH1A1CTSKCTSSCTSL | |
| SCHEMBL7201468 | 0.81 | CTSS (0.54) | ELANEATMCTSKCTSSCTSL | |
| SCHEMBL7201466 | 0.81 | CTSS (0.54) | ELANEATMCTSKCTSSCTSL | |
| SCHEMBL7202125 | 0.81 | ATM (0.54) | ELANEPRTN3ATMCTSKCTSS | |
| SCHEMBL9112663 | 0.81 | ATM (0.54) | ELANEPRTN3ATMALDH1A1CTSK | |
| SCHEMBL7202123 | 0.81 | ATM (0.54) | ELANEPRTN3ATMCTSKCTSS | |
| SCHEMBL9114401 | 0.81 | ALDH1A1 (0.57) | ELANEPRTN3ATMALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979242-A2 | SUBSTITUTED OXADIAZOLE CYSTEINE PROTEASE INHIBITORS | CORTECH, INC. (US) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049190-A2 | SUBSTITUTED OXADIAZOLE CYSTEINE PROTEASE INHIBITORS | CORTECH, INC. (US) | 1998-11-05 | — | — | WO | disclosed |