Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | DKK1 | O94907 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421078 | 0.78 | GABRA1 (0.39) | GABRA1PFKFB3DYRK1AMMP8MMP3 | |
| SCHEMBL7421349 | 0.78 | KDM4E (0.47) | GABRA1PFKFB3CA12CA1CA2 | |
| SCHEMBL4008105 | 0.77 | GABRA1 (0.61) | GABRA1PFKFB3DYRK1AMMP8MMP3 | |
| SCHEMBL7425777 | 0.75 | GABRA1 (0.37) | GABRA1PFKFB3MMP8MMP3DKK1 | |
| SCHEMBL3467794 | 0.72 | FFAR1 (0.36) | PDPK1CA1CA2CA9KDM4E | |
| SCHEMBL7082335 | 0.71 | PTGS2 (0.39) | PFKFB3CA12CA1CA2CA9 | |
| SCHEMBL27679133 | 0.70 | CCR1 (0.47) | PFKFB3CA12CA1CA2CA9 | |
| SCHEMBL3055723 | 0.69 | KDM4E (0.60) | PFKFB3MMP8MMP3KDM4ECYP1A2 | |
| SCHEMBL7422938 | 0.69 | HSD17B1 (0.39) | PFKFB3CA12CA1CA2CA9 | |
| SCHEMBL9198944 | 0.68 | L3MBTL1 (0.34) | PFKFB3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |