Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343883 | 0.89 | CA2 (0.41) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL7342267 | 0.85 | CA1 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7353691 | 0.84 | GRIA4 (0.36) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL7369396 | 0.82 | NPC1 (0.38) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL2785442 | 0.79 | DPP4 (0.47) | DPP4CYP3A4TAAR1HSD17B10TDP1 | |
| SCHEMBL7366245 | 0.73 | ALDH1A1 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9373748 | 0.73 | DPP4 (0.36) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL4602672 | 0.72 | SLC6A2 (0.43) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL9654854 | 0.72 | CA2 (0.34) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL2787849 | 0.72 | DPP4 (0.50) | DPP4CYP3A4TAAR1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |