Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | MDH1 | P40925 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033304 | 0.89 | ALDH1A1 (0.63) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8889528 | 0.88 | KMT2A (0.63) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8020109 | 0.87 | SMN1; SMN2 (0.58) | SIGMAR1FAAHALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8029605 | 0.86 | MEN1 (0.58) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8029862 | 0.86 | SMN1; SMN2 (0.58) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8029611 | 0.85 | PKM (0.67) | L3MBTL1FAAHALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8020023 | 0.84 | POLB (0.61) | SIGMAR1FAAHALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8029900 | 0.83 | LTA4H (0.57) | SIGMAR1L3MBTL1FAAHMEN1KMT2A | |
| SCHEMBL8029856 | 0.83 | FAAH (0.62) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8033251 | 0.82 | CYP2D6 (0.57) | FAAHALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |