Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134211 | 0.89 | TSHR (0.43) | MTNR1AMTNR1B | |
| SCHEMBL9155738 | 0.87 | LMNA (0.46) | MTNR1AMTNR1B | |
| SCHEMBL9134109 | 0.87 | MTNR1A (0.48) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL9134193 | 0.86 | MTNR1A (0.43) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL8032129 | 0.84 | KMT2A (0.44) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL17336421 | 0.84 | HSD17B2 (0.56) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL8860046 | 0.84 | KMT2A (0.46) | — | |
| SCHEMBL8030133 | 0.83 | ALDH1A1 (0.45) | MTNR1AMTNR1B | |
| SCHEMBL9131869 | 0.83 | ALDH1A1 (0.42) | HSD17B2HSD17B1 | |
| SCHEMBL9135359 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BHSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663204-A | CHOLECYSTOKININ AND GASTRIN ANTAGONIST FOR APPETITE REGULATORS, GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-09-02 | — | — | US | disclosed |
| US-5625066-A | Optically active hydroquinine (amino-3 phenyl)-1 ethanesulfonate, preparation and use thereof | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |
| US-5523469-A | REACTING ALKALI METAL SULFITE ON 1-(1-BROMOETHYL)-3-NITROBENZENE; CONVERSION TO POTASSIUM SALT; CONVERSION TO BENZYLQUINIUM SALT; THEN QUATERNIZATION | RHONE-POULENC RORER S.A. (FR) | 1996-06-04 | — | — | US | disclosed |
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |