SCHEMBL8030263

SCHEMBL8030263

CC(C)(C)c1ccc([Se+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
LMNA P02545 2/20 0.42
TYR P14679 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RAB9A P51151 5/20 0.38
SRD5A2 P31213 1/20 0.38
KCNK9 Q9NPC2 1/20 0.37
ALDH1A1 P00352 4/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
KIF11 P52732 2/20 0.37
CYP3A4 P08684 1/20 0.37
NPC1 O15118 3/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5462570 0.90 TSHR (0.52) TSHRLMNATYRMAPTTDP1
Trifluoromethanesulfonic Acid SCHEMBL29834793 0.82 HSD11B1 (0.41) TDP1RAB9AALDH1A1NPC1HSD11B1
Tert-Butylbenzene SCHEMBL2568053 0.76 MAPK1 (0.55) TSHRLMNATYRL3MBTL1MAPT
Tert-Butylbenzene SCHEMBL18889 0.76 MAPK1 (0.55) TSHRLMNATYRL3MBTL1MAPT
Tert-Butylbenzene SCHEMBL337648 0.76 MAPK1 (0.55) TSHRLMNATYRL3MBTL1MAPT
Tert-Butylbenzene SCHEMBL22264597 0.76 MAPK1 (0.55) TSHRLMNATYRL3MBTL1MAPT
Tert-Butylbenzene SCHEMBL22264599 0.76 MAPK1 (0.55) TSHRLMNATYRL3MBTL1MAPT
SCHEMBL1093222 0.76 ALDH1A1 (0.40) TSHRLMNAMAPTTDP1ALDH1A1
Tert-Butylbenzene SCHEMBL6537004 0.73 MAPK1 (0.52) TSHRLMNATYRL3MBTL1MAPT
Tert-Butylbenzene SCHEMBL309340 0.73 LMNA (0.55) TSHRLMNATYRL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985165-A1 IONIC HALOMETHYL-1,3,5-TRIAZINE PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-03-15 EP disclosed
US-5847133-A Ionic halomethyl-1,3,5-triazine photoinitiators MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-08 US disclosed
WO-1998053369-A1 IONIC HALOMETHYL-1,3,5-TRIAZINE PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-11-26 WO disclosed