Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777232 | 0.79 | MAOA (0.40) | RAB9ANPC1ALDH1A1MAPTMAOA | |
| SCHEMBL10644798 | 0.77 | MAOA (0.43) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL8021260 | 0.77 | MLYCD (0.41) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL8034515 | 0.77 | ALDH1A1 (0.52) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL8669085 | 0.77 | NR1H2 (0.44) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL3115384 | 0.77 | SMN1; SMN2 (0.44) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL10577476 | 0.77 | — | — | |
| SCHEMBL22242836 | 0.77 | LMNA (0.41) | KMT2AMEN1ALDH1A1MAPTIDO1 | |
| SCHEMBL779142 | 0.76 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1MAPTMAOA | |
| SCHEMBL7245394 | 0.74 | SLC6A2 (0.50) | RAB9AKMT2ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645355-B1 | Method for the preparation of trifluoroethyl sulphur compounds from thiolates and 1-chloro-2,2,2-trifluoroethane | SOLVAY (BE) | 2000-03-22 | — | — | EP | disclosed |
| US-5534634-A | Process for preparing trifluoroethyl sulfur compounds from thiolates and 1-chloro-2,2,2-trifluoroethane | HOECHST AG (DE) | 1996-07-09 | — | — | US | disclosed |
| EP-0645355-A1 | Method for the preparation of trifluoroethyl sulphur compounds from thiolates and 1-chloro-2,2,2-trifluoroethane | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-29 | — | — | EP | disclosed |