SCHEMBL779142

SCHEMBL779142

FC(F)(F)CSc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPK1 P28482 1/20 0.52
FFAR1 O14842 1/20 0.43
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MGLL Q99685 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
TSHR P16473 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
MTNR1A P48039 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL10963462 0.84 ALDH1A1 (0.39) ALDH1A1MAPK1FFAR1MAOAMAOB
Propane SCHEMBL10964305 0.82 ALDH1A1 (0.36) ALDH1A1MAPK1FFAR1MAOAMAOB
SCHEMBL776327 0.81 ALDH1A1 (0.48) ALDH1A1MAPK1FFAR1MAOAMAOB
SCHEMBL777232 0.78 MAOA (0.40) ALDH1A1MAOAMAOBSMN1; SMN2MAPT
SCHEMBL8021260 0.76 MLYCD (0.41) ALDH1A1MAPK1MAPTHPGDTSHR
SCHEMBL8034515 0.76 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTCYP3A4TSHR
SCHEMBL28477956 0.76 TRPV4 (0.31)
SCHEMBL8669085 0.76 NR1H2 (0.44) ALDH1A1MAPTHPGDHSD17B10CYP3A4
SCHEMBL8030618 0.76 RAB9A (0.42) ALDH1A1MAOAMAOBSMN1; SMN2MAPT
SCHEMBL776637 0.76 ALDH1A1 (0.61) ALDH1A1MAPK1FFAR1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117049997-A Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof 帕潘纳(北京)科技有限公司 2023-11-14 CN claimed
US-4643811-A PHOTOCHLORINATION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-02-17 US claimed
EP-0200657-A1 Process for the preparation of trifluoroethoxy- or trifluoroethylthiobenzenes RHONE-POULENC CHIMIE (FR) 1986-11-05 EP claimed
CN-117049997-B Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof 帕潘纳(北京)科技有限公司 2025-12-05 CN disclosed
CN-117049997-B Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof 帕潘纳(北京)科技有限公司 2025-12-05 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
EP-4297752-A2 MESCALINE DERIVATIVES WITH MODIFIED ACTION Mind Medicine, Inc. (US) 2024-01-03 EP disclosed
CN-117049997-A Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof 帕潘纳(北京)科技有限公司 2023-11-14 CN disclosed
CN-117049997-A Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof 帕潘纳(北京)科技有限公司 2023-11-14 CN disclosed
US-20230227398-A1 MESCALINE DERIVATIVES WITH MODIFIED ACTION Mind Medicine, Inc. (US) 2023-07-20 US disclosed
EP-0200657-A1 Process for the preparation of trifluoroethoxy- or trifluoroethylthiobenzenes RHONE-POULENC CHIMIE (FR) 1986-11-05 EP disclosed
EP-0197868-A1 Process for the preparation of dichlorotrifluoroethoxy and ethylthioaromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-10-15 EP disclosed
US-4534788-A CONTROLLING WEEDS IN WHEAT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-13 US disclosed
EP-0064322-B1 BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-22 EP disclosed
US-4452628-A TRIAZINYL BENZENE SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-05 US disclosed
EP-0023422-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP disclosed
EP-0064322-A2 Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-10 EP disclosed
EP-0057546-A2 Sulfonylurea N-oxides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-11 EP disclosed
EP-0023422-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227398-A1 MESCALINE DERIVATIVES WITH MODIFIED ACTION CHRM5, CHRM1, DRD3 ALDH1A1 400/4885MAPK1 3883/4885FFAR1 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.