Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043013 | 0.87 | MAPK1 (0.41) | POLBKAT2BGAAMAPK1RXFP1 | |
| SCHEMBL8200499 | 0.80 | ALDH1A1 (0.55) | POLBKAT2BGAALMNAALDH1A1 | |
| SCHEMBL8340870 | 0.78 | GAA (0.62) | POLBGAAMAPK1LMNAALDH1A1 | |
| SCHEMBL8041727 | 0.78 | MAPT (0.49) | POLBMAPK1LMNAALDH1A1MAPT | |
| SCHEMBL4692876 | 0.76 | KAT2B (0.49) | POLBKAT2BGAAMAPK1LMNA | |
| SCHEMBL8090673 | 0.75 | SERPINE1 (0.55) | POLBGAAMAPK1LMNAALDH1A1 | |
| SCHEMBL27499600 | 0.75 | ALDH1A1 (0.41) | POLBGAAMAPK1LMNAALDH1A1 | |
| SCHEMBL15577144 | 0.73 | GAA (0.51) | POLBKAT2BGAAMAPK1LMNA | |
| SCHEMBL22636966 | 0.71 | AR (0.42) | MAPK1RXFP1LMNAALDH1A1MAPT | |
| SCHEMBL8194643 | 0.71 | MEN1 (0.42) | MAPK1LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993461-A1 | NEW QUINOXALINE DIONE DERIVATIVES, THE PRODUCTION THEREOF AND USE OF THE SAME IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999000384-A1 | NEW QUINOXALINE DIONE DERIVATIVES, THE PRODUCTION THEREOF AND USE OF THE SAME IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |