SCHEMBL8031377

SCHEMBL8031377

C#CCOc1cc(-c2nn(C)c(SC)c2C)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.38
EGFR P00533 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8035641 0.83 HSP90AA1 (0.34) PGK1
SCHEMBL7692799 0.83 PGK1 (0.38) PGK1EGFRLMNA
SCHEMBL8031283 0.82 PGK1 (0.35) PGK1EGFRLMNA
SCHEMBL8038089 0.82 PGK1 (0.35) PGK1EGFRLMNA
SCHEMBL8621119 0.80 PGK1 (0.41) PGK1LMNA
SCHEMBL6906104 0.78 PGK1 (0.37) PGK1EGFRLMNA
SCHEMBL8021916 0.76 DRD2 (0.32)
SCHEMBL6292288 0.76 PGK1 (0.35) PGK1EGFRLMNA
SCHEMBL8356733 0.76 PGK1 (0.35) PGK1EGFRLMNA
SCHEMBL8022013 0.76 POLB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103667-A Phenylpyrazole herbicides NOVARTIS CORPORATION (US) 2000-08-15 US disclosed
EP-0832070-A1 NOVEL HERBICIDES Novartis AG (CH) 1998-04-01 EP disclosed
WO-1997000246-A1 NOVEL HERBICIDES NOVARTIS AG (CH) 1997-01-03 WO disclosed