Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998849 | 0.79 | TSHR (0.56) | ALDH1A1MAPTCYP3A4MAPK1MEN1 | |
| SCHEMBL29379293 | 0.79 | TSHR (0.56) | ALDH1A1MAPTCYP3A4MAPK1MEN1 | |
| SCHEMBL8041974 | 0.78 | MAPT (0.58) | ALDH1A1MAPTCYP3A4MEN1LMNA | |
| SCHEMBL21885660 | 0.78 | GPR35 (0.56) | ALDH1A1MAPTKDM4ECYP3A4MAPK1 | |
| SCHEMBL18607548 | 0.78 | VCAM1 (0.51) | MAPTMAPK1TDP1 | |
| SCHEMBL229248 | 0.75 | TDP1 (0.59) | ALDH1A1CYP2D6MAPTKDM4ECYP3A4 | |
| SCHEMBL31190183 | 0.75 | TDP1 (0.59) | ALDH1A1CYP2D6MAPTKDM4ECYP3A4 | |
| SCHEMBL18956859 | 0.74 | MAPT (0.51) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL30072759 | 0.74 | MAPT (0.51) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL21885659 | 0.74 | GPR35 (0.56) | ALDH1A1MAPTKDM4ECYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |