Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033201 | 0.93 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2APKMMAPK1 | |
| SCHEMBL8029641 | 0.85 | ALDH1A1 (0.65) | PPARGPPARALMNAPOLBALDH1A1 | |
| SCHEMBL8035787 | 0.80 | FAAH (0.54) | LMNAPOLBALDH1A1KMT2APKM | |
| SCHEMBL8031501 | 0.78 | SIGMAR1 (0.52) | PPARGPPARALMNAALDH1A1KMT2A | |
| SCHEMBL8020083 | 0.78 | ALDH1A1 (0.63) | PPARALMNAALDH1A1KMT2APKM | |
| SCHEMBL8033286 | 0.76 | PKM (0.67) | LMNAPOLBALDH1A1KMT2APKM | |
| SCHEMBL3102154 | 0.74 | PPARA (0.64) | PPARGPPARALMNAALDH1A1KMT2A | |
| SCHEMBL8186898 | 0.74 | ALDH1A1 (0.74) | LMNAALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL8029636 | 0.74 | SIGMAR1 (0.59) | PPARGPPARALMNAPOLBALDH1A1 | |
| SCHEMBL8031485 | 0.73 | FAAH (0.61) | LMNAPOLBALDH1A1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |