Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038358 | 0.88 | HPGD (0.39) | APPALDH1A1HPGD | |
| SCHEMBL8035589 | 0.82 | TRPV1 (0.41) | APPLMNAALDH1A1POLBHPGD | |
| SCHEMBL8034976 | 0.81 | NPC1 (0.45) | APPALDH1A1HPGD | |
| SCHEMBL8035761 | 0.81 | THRA (0.38) | APPALDH1A1HPGDGAACYP1A2 | |
| SCHEMBL8034162 | 0.80 | LRRK2 (0.38) | APPLMNAALDH1A1POLBHPGD | |
| SCHEMBL8035765 | 0.79 | APP (0.38) | APPLMNAALDH1A1HPGDGAA | |
| SCHEMBL8037415 | 0.79 | S1PR1 (0.41) | APPACHEALDH1A1POLBHPGD | |
| SCHEMBL8036048 | 0.79 | KDM1A (0.43) | APPLMNAACHEALDH1A1HPGD | |
| SCHEMBL8034159 | 0.77 | ALDH1A1 (0.44) | LMNAALDH1A1HPGDGAAMAPT | |
| SCHEMBL8041701 | 0.75 | APP (0.38) | APPLMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |