Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033664 | 0.89 | RAB9A (0.39) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL8050904 | 0.85 | ALDH1A1 (0.33) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL8047429 | 0.83 | ALDH1A1 (0.30) | ALDH1A1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8044718 | 0.81 | ALDH1A1 (0.31) | KMT2AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8043479 | 0.81 | — | — | |
| SCHEMBL8032728 | 0.79 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL8050076 | 0.78 | MEN1 (0.33) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL8048727 | 0.78 | CYP1A2 (0.43) | ALDH1A1MAPTRAB9AALOX15HSD17B10 | |
| SCHEMBL8042516 | 0.76 | — | — | |
| SCHEMBL8048326 | 0.76 | TP53 (0.37) | KMT2AALDH1A1MAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |