Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043479 | 0.84 | — | — | |
| SCHEMBL8047429 | 0.82 | ALDH1A1 (0.30) | ALDH1A1RAB9A | |
| SCHEMBL8044718 | 0.80 | ALDH1A1 (0.31) | KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL8033664 | 0.80 | RAB9A (0.39) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8032733 | 0.78 | KMT2A (0.33) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8042516 | 0.77 | — | — | |
| SCHEMBL8032541 | 0.77 | LMNA (0.33) | MEN1KMT2AMAPTRECQL | |
| SCHEMBL8032506 | 0.76 | — | — | |
| SCHEMBL8042402 | 0.72 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL8043551 | 0.71 | SMN1; SMN2 (0.51) | MEN1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |