Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | UBE2M | P61081 | 5/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048338 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL8033923 | 0.85 | ALDH1A1 (0.38) | ALDH1A1UBE2MDCUN1D1HTTKMT2A | |
| SCHEMBL8052246 | 0.83 | KMT2A (0.36) | ALDH1A1HTTKMT2AMEN1NPSR1 | |
| SCHEMBL8032337 | 0.81 | HTT (0.39) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL8045327 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL8043561 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AGAATSHR | |
| SCHEMBL8032733 | 0.79 | KMT2A (0.33) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL8033860 | 0.78 | DCUN1D1 (0.36) | UBE2MDCUN1D1 | |
| SCHEMBL8044008 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL8047501 | 0.78 | L3MBTL1 (0.37) | ALDH1A1HTTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |