Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12774293 | 0.82 | MAPT (0.40) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL1041826 | 0.76 | MAPT (0.39) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL8035462 | 0.73 | ALDH1A1 (0.35) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL12774284 | 0.73 | CA2 (0.38) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL12774288 | 0.73 | GABRA1 (0.38) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL1043157 | 0.72 | ACP1 (0.39) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL3786708 | 0.70 | GAA (0.52) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL3665710 | 0.69 | TDP1 (0.39) | MAPTGAAKDM4EHTR6ALDH1A1 | |
| SCHEMBL6285846 | 0.69 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL28279 | 0.69 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084133-A | REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY | KANKYO KAGAKU CENTER CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |