SCHEMBL8033737

SCHEMBL8033737

C=C(N)Cc1ccccc1[Sn]

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
AKR1B1 P15121 1/20 0.30
HSPA5 P11021 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
PARP1 P09874 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033732 1.00 PKM (0.35) PKMLMNASMN1; SMN2TAAR1AKR1B1
SCHEMBL6525138 0.84 PKM (0.41) PKMLMNASMN1; SMN2TAAR1AKR1B1
SCHEMBL10535293 0.76 AKR1B1 (0.56) PKMLMNASMN1; SMN2TAAR1AKR1B1
SCHEMBL10831200 0.76 FDPS (0.40) PKMLMNASMN1; SMN2TAAR1AKR1B1
SCHEMBL26429489 0.74 TAAR1 (0.48) TAAR1MAPTTSHR
SCHEMBL27561888 0.74 TAAR1 (0.50) LMNATAAR1
SCHEMBL22296120 0.74 GABRA1 (0.43) PKMLMNASMN1; SMN2AKR1B1MAPT
SCHEMBL6048574 0.71 DPP4 (0.55) LMNACYP2C19HSD17B10
SCHEMBL9941584 0.71 LIPG (0.47) PKMLMNASMN1; SMN2
SCHEMBL6401722 0.69 FOLH1 (0.52) SMN1; SMN2MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022822-A Organotin compound and catalyst for transesterification comprising the same RYOJI NOYORI (JP) 2000-02-08 US disclosed