Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 20/20 | 0.36 |
| ▸ | UBE2M | P61081 | 19/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032337 | 0.87 | HTT (0.39) | — | |
| SCHEMBL8042403 | 0.86 | DCUN1D1 (0.38) | DCUN1D1UBE2MKDM1A | |
| SCHEMBL8052246 | 0.85 | KMT2A (0.36) | — | |
| SCHEMBL8044008 | 0.84 | ALDH1A1 (0.42) | — | |
| SCHEMBL8045327 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL8047183 | 0.81 | — | — | |
| SCHEMBL8032728 | 0.78 | ALDH1A1 (0.37) | DCUN1D1UBE2M | |
| SCHEMBL8047970 | 0.78 | HTT (0.39) | — | |
| SCHEMBL8046340 | 0.77 | KMT2A (0.34) | — | |
| SCHEMBL8043236 | 0.77 | UBE2M (0.35) | DCUN1D1UBE2MKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |