Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 19/20 | 0.38 |
| ▸ | UBE2M | P61081 | 18/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033860 | 0.86 | DCUN1D1 (0.36) | DCUN1D1UBE2MKDM1A | |
| SCHEMBL8042957 | 0.86 | HTT (0.41) | LMNAKMT2A | |
| SCHEMBL8050969 | 0.83 | KMT2A (0.39) | LMNAKMT2A | |
| SCHEMBL8712546 | 0.83 | ALDH1A1 (0.44) | LMNAKMT2A | |
| SCHEMBL8042707 | 0.80 | ALDH1A1 (0.46) | LMNAKMT2A | |
| SCHEMBL8033637 | 0.79 | LMNA (0.32) | LMNAKMT2A | |
| SCHEMBL8033677 | 0.77 | ALDH1A1 (0.54) | DCUN1D1UBE2MLMNAKMT2A | |
| SCHEMBL8042045 | 0.77 | UBE2M (0.46) | DCUN1D1UBE2MKDM1A | |
| SCHEMBL8046043 | 0.76 | HTT (0.42) | LMNAKMT2A | |
| SCHEMBL8033923 | 0.75 | ALDH1A1 (0.38) | DCUN1D1UBE2MLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |