Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032337 | 0.87 | HTT (0.39) | ALDH1A1CYP2C19LMNAKMT2AUSP2 | |
| SCHEMBL8712546 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8052246 | 0.85 | KMT2A (0.36) | ALDH1A1TP53LMNASMN1; SMN2KMT2A | |
| SCHEMBL8033860 | 0.84 | DCUN1D1 (0.36) | — | |
| SCHEMBL8045327 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TP53CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL8047183 | 0.81 | — | — | |
| SCHEMBL8032728 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TP53LMNASMN1; SMN2KMT2A | |
| SCHEMBL8047970 | 0.78 | HTT (0.39) | ALDH1A1TP53LMNASMN1; SMN2KMT2A | |
| SCHEMBL8046340 | 0.77 | KMT2A (0.34) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8048338 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TP53LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |