Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342794 | 0.87 | BRD4 (0.68) | BRD4KMT2ATDP1L3MBTL1HDAC1 | |
| SCHEMBL7043590 | 0.81 | LTA4H (0.62) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12322221 | 0.81 | SGMS2 (0.53) | BRD4KMT2AL3MBTL1SYKGAA | |
| SCHEMBL8577017 | 0.81 | HTR1A (0.46) | SYKNPFFR1NPFFR2CYP2C9SIGMAR1 | |
| SCHEMBL8030272 | 0.80 | KMT2A (0.48) | KMT2ATDP1L3MBTL1POLBGAA | |
| SCHEMBL6432668 | 0.80 | HDAC1 (0.46) | KMT2AHDAC1POLBSMN1; SMN2 | |
| SCHEMBL10845357 | 0.78 | MAPT (0.47) | KMT2ATDP1HDAC1POLBGAA | |
| SCHEMBL29193980 | 0.78 | LMNA (0.45) | KMT2AHDAC1POLBNPFFR1NPFFR2 | |
| SCHEMBL294159 | 0.78 | BRD4 (0.54) | BRD4KMT2ATDP1L3MBTL1HDAC1 | |
| SCHEMBL30705048 | 0.78 | BRD4 (0.54) | BRD4KMT2ATDP1L3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5919824-A | Aminophenol derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |