Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540588 | 0.92 | NQO2 (0.53) | HTR1ADRD2NQO2PTGER1PTGER4 | |
| SCHEMBL8985088 | 0.85 | MTNR1A (0.54) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8573380 | 0.83 | SIGMAR1 (0.54) | TAAR1NPFFR1NPFFR2SIGMAR1IDO1 | |
| SCHEMBL8033873 | 0.81 | BRD4 (0.59) | NPFFR1NPFFR2SYKSIGMAR1CYP2C9 | |
| SCHEMBL30544325 | 0.79 | SYK (0.57) | NPFFR1NPFFR2SYKIDO1 | |
| SCHEMBL7866386 | 0.79 | NQO2 (0.48) | NQO2TAAR1IDO1 | |
| SCHEMBL24815312 | 0.78 | SIGMAR1 (0.58) | NPFFR1NPFFR2SIGMAR1IDO1CYP2C9 | |
| SCHEMBL28075068 | 0.78 | HTR1A (0.49) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL22657971 | 0.78 | SYK (0.56) | NPFFR1NPFFR2SYKIDO1 | |
| SCHEMBL12322221 | 0.78 | SGMS2 (0.53) | SYKSIGMAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853713-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5618528-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0748226-A1 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995022991-A2 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1995-08-31 | — | — | WO | disclosed |