Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051083 | 0.92 | ALOX5 (0.39) | HTR1AHTR2AHTR7RAB9AHTT | |
| SCHEMBL8051217 | 0.87 | EIF4E (0.36) | HTR1AHTR2AHTR7RAB9ASMN1; SMN2 | |
| SCHEMBL8032515 | 0.85 | HTR1A (0.43) | HTR1AHTR2AHTR7RAB9AHTT | |
| SCHEMBL8031825 | 0.85 | LMNA (0.40) | RAB9AHTTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8050718 | 0.78 | HTT (0.51) | HTR1AHTR2AHTR7HTTSMN1; SMN2 | |
| SCHEMBL8033675 | 0.78 | TSHR (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL8046090 | 0.77 | TSHR (0.52) | HTTSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL8049124 | 0.76 | TSHR (0.60) | HTTSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL8032636 | 0.76 | ATM (0.47) | RAB9AHTTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8709945 | 0.76 | ALDH1A1 (0.52) | RAB9AHTTNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |