Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032814 | 0.89 | NAMPT (0.39) | CYP1A2POLBMAPTNAMPTRAB9A | |
| SCHEMBL8037293 | 0.88 | LMNA (0.49) | LMNACYP1A2POLBMAPTGAA | |
| SCHEMBL8032185 | 0.86 | LMNA (0.45) | LMNACYP1A2POLBMAPTGAA | |
| SCHEMBL4014827 | 0.85 | NAMPT (0.37) | LMNACYP1A2POLBMAPTGAA | |
| SCHEMBL8038397 | 0.83 | TARBP2 (0.49) | LMNACYP1A2POLBMAPTTARBP2 | |
| SCHEMBL8036404 | 0.83 | CYP1A2 (0.43) | LMNACYP1A2POLBMAPTGAA | |
| SCHEMBL8034697 | 0.79 | MAPT (0.40) | LMNACYP1A2POLBMAPTGAA | |
| SCHEMBL4008878 | 0.78 | KDM4E (0.45) | LMNACYP1A2POLBGAANPSR1 | |
| SCHEMBL4007701 | 0.77 | CTRC (0.41) | CYP1A2POLBMAPTGAANAMPT | |
| SCHEMBL8030988 | 0.74 | KDM4E (0.53) | LMNACYP1A2POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |