Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010263 | 0.87 | DHPS (0.41) | NAMPTCYP1A2POLBMAPTLMNA | |
| SCHEMBL8034254 | 0.85 | LMNA (0.42) | NAMPTCYP1A2POLBMAPTLMNA | |
| SCHEMBL8032814 | 0.82 | NAMPT (0.39) | NAMPTCYP1A2POLBMAPTRAB9A | |
| SCHEMBL4007708 | 0.78 | CYP1A2 (0.40) | NAMPTCYP1A2POLBMAPTRAB9A | |
| SCHEMBL4008882 | 0.78 | KCNH2 (0.39) | CYP1A2POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL8037293 | 0.77 | LMNA (0.49) | CYP1A2POLBMAPTLMNARAB9A | |
| SCHEMBL4011727 | 0.75 | RAB9A (0.41) | CYP1A2MAPTLMNARAB9AALDH1A1 | |
| SCHEMBL4014170 | 0.74 | MAPT (0.43) | CYP1A2POLBMAPTLMNARAB9A | |
| SCHEMBL4008878 | 0.73 | KDM4E (0.45) | CYP1A2POLBLMNARAB9AALDH1A1 | |
| SCHEMBL4009317 | 0.72 | CNR1 (0.40) | CYP1A2POLBMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |