Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042522 | 0.85 | MAPT (0.36) | MAPTSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL8044772 | 0.82 | MAPT (0.38) | MAPTSMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL8051249 | 0.78 | RAB9A (0.35) | MAPTSMN1; SMN2RECQLKDM4EALDH1A1 | |
| SCHEMBL8044880 | 0.77 | GCK (0.39) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8044639 | 0.76 | HDAC6 (0.49) | MAPTSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL8043035 | 0.76 | MAPT (0.33) | MAPTUSP7KDM4EALDH1A1POLB | |
| SCHEMBL8043892 | 0.75 | MAPT (0.38) | MAPTSMN1; SMN2MEN1KMT2AUSP7 | |
| SCHEMBL8033927 | 0.74 | NPSR1 (0.40) | MAPTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL8033964 | 0.74 | SMN1; SMN2 (0.39) | MAPTSMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL8043559 | 0.73 | MAPT (0.34) | MAPTUSP7ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |