Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042522 | 0.79 | MAPT (0.36) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8051249 | 0.79 | RAB9A (0.35) | HSD17B10ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8034259 | 0.77 | MAPT (0.35) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8033927 | 0.75 | NPSR1 (0.40) | HSD17B10ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8044639 | 0.75 | HDAC6 (0.49) | L3MBTL1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL8043035 | 0.75 | MAPT (0.33) | ALDH1A1KDM4EMAPTLMNAPOLB | |
| SCHEMBL8033964 | 0.75 | SMN1; SMN2 (0.39) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8043559 | 0.74 | MAPT (0.34) | ALDH1A1MAPTPOLB | |
| SCHEMBL8037035 | 0.74 | CYP1A2 (0.34) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8043580 | 0.74 | HTT (0.43) | HSD17B10ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |