Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034259 | 0.85 | MAPT (0.35) | MAPTALDH1A1POLBKDM4ETSHR | |
| SCHEMBL8044639 | 0.81 | HDAC6 (0.49) | MAPTALDH1A1POLBKDM4ETSHR | |
| SCHEMBL8051249 | 0.80 | RAB9A (0.35) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL8044880 | 0.79 | GCK (0.39) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL8043559 | 0.78 | MAPT (0.34) | MAPTALDH1A1POLBUSP7 | |
| SCHEMBL8043918 | 0.76 | MAPT (0.45) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL8033927 | 0.76 | NPSR1 (0.40) | MAPTALDH1A1POLBHPGDMEN1 | |
| SCHEMBL8033964 | 0.76 | SMN1; SMN2 (0.39) | MAPTALDH1A1POLBTP53SMN1; SMN2 | |
| SCHEMBL8043035 | 0.76 | MAPT (0.33) | MAPTALDH1A1POLBKDM4EUSP7 | |
| SCHEMBL8032850 | 0.75 | MAPT (0.37) | MAPTALDH1A1POLBUSP7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |