Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119744 | 0.75 | ADORA3 (0.58) | SMN1; SMN2LMNAHTTL3MBTL1MEN1 | |
| SCHEMBL9852280 | 0.73 | ALDH1A1 (0.69) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL4242407 | 0.73 | RAB9A (0.61) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL24804634 | 0.72 | ALDH1A1 (0.58) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10591917 | 0.72 | RAB9A (0.76) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11508630 | 0.70 | HDAC4 (0.52) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9396687 | 0.69 | HTT (0.45) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL15219305 | 0.69 | NOS2 (0.53) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL28931524 | 0.68 | GAA (0.56) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL3298289 | 0.68 | KCNH3 (0.73) | GAAALDH1A1LMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114537-A | 1,2,4-THIADIAZOLE COMPOUND IS USEFUL FOR TRAPPING THIOL COMPOUNDS AND SELECTIVELY CHANGING THIOLS TO DISULFIDE COMPOUNDS | APOTEX INC. (CA) | 2000-09-05 | — | — | US | disclosed |
| CN-1216527-A | Method for scavenging mercaptan | APOTEX INC (CA) | 1999-05-12 | — | — | CN | disclosed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |