Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8036033 | 1.00 | GAA (0.43) | GAALMNAALDH1A1ERN1MAPT | |
| Cyclohexylamine SCHEMBL7802264 | 0.88 | GAA (0.47) | GAALMNAALDH1A1ERN1MAPT | |
| Cyclohexylamine SCHEMBL7792901 | 0.86 | ERN1 (0.48) | GAALMNAALDH1A1ERN1MAPT | |
| Cyclohexylamine SCHEMBL8035138 | 0.84 | GRIK1 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4EKMO | |
| Cyclohexylamine SCHEMBL8035135 | 0.84 | GRIK1 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4EKMO | |
| Cyclohexylamine SCHEMBL8035226 | 0.84 | VCAM1 (0.53) | GAALMNAALDH1A1MAPTSMN1; SMN2 | |
| Cyclohexylamine SCHEMBL8035231 | 0.84 | VCAM1 (0.53) | GAALMNAALDH1A1MAPTSMN1; SMN2 | |
| 3-Nitrobenzaldehyde SCHEMBL8039156 | 0.83 | KMO (0.46) | LMNAALDH1A1MAPTSMN1; SMN2KMO | |
| 3-Nitrobenzaldehyde SCHEMBL8039154 | 0.83 | KMO (0.46) | LMNAALDH1A1MAPTSMN1; SMN2KMO | |
| Lysine SCHEMBL8025632 | 0.78 | GSR (0.46) | ERN1MAPTKMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |