Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GRM8 | O00222 | 5/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.41 |
| ▸ | GRM6 | O15303 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Nitrobenzaldehyde SCHEMBL8039156 | 1.00 | KMO (0.46) | KMOHPGDTHRBEPHX1MAPT | |
| 3-Nitrobenzaldehyde SCHEMBL8035795 | 0.89 | KMO (0.43) | KMOHPGDTHRBEPHX1MAPT | |
| 3-Nitrobenzaldehyde SCHEMBL8035793 | 0.89 | KMO (0.43) | KMOHPGDTHRBEPHX1MAPT | |
| 3-Nitrobenzaldehyde SCHEMBL7793140 | 0.89 | HPGD (0.47) | HPGDTHRBEPHX1MAPTALDH1A1 | |
| Cyclohexylamine SCHEMBL8035135 | 0.88 | GRIK1 (0.46) | KMOEPHX1MAPTALDH1A1GRM8 | |
| Cyclohexylamine SCHEMBL8035138 | 0.88 | GRIK1 (0.46) | KMOEPHX1MAPTALDH1A1GRM8 | |
| 3-Nitrobenzaldehyde SCHEMBL7793079 | 0.86 | NFE2L2 (0.49) | HPGDTHRBMAPTALDH1A1POLB | |
| Benzaldehyde SCHEMBL8035694 | 0.84 | KIF11 (0.42) | THRBALDH1A1 | |
| Cyclohexylamine SCHEMBL8036033 | 0.83 | GAA (0.43) | KMOHPGDMAPTALDH1A1LMNA | |
| Cyclohexylamine SCHEMBL8036036 | 0.83 | GAA (0.43) | KMOHPGDMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |