Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035135 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2EPHX1ALDH1A1SMN1; SMN2 | |
| Lysine SCHEMBL7803085 | 0.88 | MMP2 (0.43) | GRIK1GRIK2EPHX1ALDH1A1SMN1; SMN2 | |
| Lysine SCHEMBL7803083 | 0.88 | MMP2 (0.43) | GRIK1GRIK2EPHX1ALDH1A1SMN1; SMN2 | |
| 3-Nitrobenzaldehyde SCHEMBL8039156 | 0.88 | KMO (0.46) | EPHX1ALDH1A1SMN1; SMN2GRM8GRM6 | |
| 3-Nitrobenzaldehyde SCHEMBL8039154 | 0.88 | KMO (0.46) | EPHX1ALDH1A1SMN1; SMN2GRM8GRM6 | |
| Cyclohexylamine SCHEMBL7800696 | 0.87 | ALDH1A1 (0.43) | EPHX1ALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| Lysine SCHEMBL8039332 | 0.85 | MMP2 (0.41) | GRIK1GRIK2EPHX1ALDH1A1SMN1; SMN2 | |
| Lysine SCHEMBL8025522 | 0.85 | MMP2 (0.41) | GRIK1GRIK2EPHX1ALDH1A1SMN1; SMN2 | |
| Cyclohexylamine SCHEMBL8025550 | 0.85 | ALDH5A1 (0.42) | ALDH1A1GRM8GRM6GRM4KDM4E | |
| Cyclohexylamine SCHEMBL8025542 | 0.85 | ALDH5A1 (0.42) | ALDH1A1GRM8GRM6GRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |