Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035226 | 1.00 | VCAM1 (0.53) | VCAM1MAPTGRM8GRM6GRM4 | |
| Cyclohexylamine SCHEMBL7801777 | 0.89 | VCAM1 (0.58) | VCAM1MAPTMAPK1RAB9AALDH1A1 | |
| Cyclohexylamine SCHEMBL7792908 | 0.87 | VCAM1 (0.70) | VCAM1MAPTMAPK1RAB9AALDH1A1 | |
| Cyclohexylamine SCHEMBL8025542 | 0.87 | ALDH5A1 (0.42) | VCAM1MAPTGRM8GRM6GRM4 | |
| Cyclohexylamine SCHEMBL8025550 | 0.87 | ALDH5A1 (0.42) | VCAM1MAPTGRM8GRM6GRM4 | |
| Cyclohexylamine SCHEMBL8035138 | 0.84 | GRIK1 (0.46) | MAPTGRM8GRM6GRM4ALDH1A1 | |
| Cyclohexylamine SCHEMBL8035135 | 0.84 | GRIK1 (0.46) | MAPTGRM8GRM6GRM4ALDH1A1 | |
| Cyclohexylamine SCHEMBL8036033 | 0.84 | GAA (0.43) | MAPTALDH1A1HTTGAAKMT2A | |
| Cyclohexylamine SCHEMBL8036036 | 0.84 | GAA (0.43) | MAPTALDH1A1HTTGAAKMT2A | |
| 3-Nitrobenzaldehyde SCHEMBL8039156 | 0.81 | KMO (0.46) | MAPTGRM8GRM6GRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |