Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053395 | 0.94 | SIGMAR1 (0.58) | TMEM97SIGMAR1ACKR3NPC1RAB9A | |
| SCHEMBL8048207 | 0.93 | SIGMAR1 (0.45) | TMEM97SIGMAR1ACKR3NPC1RAB9A | |
| SCHEMBL8053417 | 0.87 | SIGMAR1 (0.47) | TMEM97SIGMAR1ACKR3NPC1RAB9A | |
| SCHEMBL8047896 | 0.84 | NPC1 (0.45) | TMEM97SIGMAR1ACKR3NPC1RAB9A | |
| SCHEMBL8047459 | 0.84 | NPC1 (0.49) | TMEM97SIGMAR1NPC1RAB9AKMT2A | |
| SCHEMBL8787114 | 0.81 | ALDH1A1 (0.41) | TMEM97SIGMAR1NPC1ALDH1A1LMNA | |
| SCHEMBL8050607 | 0.81 | SIGMAR1 (0.50) | TMEM97SIGMAR1ACKR3NPC1RAB9A | |
| SCHEMBL8046936 | 0.77 | NAMPT (0.46) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8053562 | 0.77 | HPGD (0.42) | TMEM97SIGMAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL8787321 | 0.76 | APP (0.43) | TMEM97SIGMAR1ACKR3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |