Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050607 | 0.95 | SIGMAR1 (0.50) | NPC1RAB9ATMEM97SIGMAR1ACKR3 | |
| SCHEMBL8053562 | 0.93 | HPGD (0.42) | NPC1RAB9ATMEM97SIGMAR1CCR6 | |
| SCHEMBL8046943 | 0.88 | CCR6 (0.47) | NPC1RAB9ATMEM97SIGMAR1ACKR3 | |
| SCHEMBL8053341 | 0.85 | RAB9A (0.47) | NPC1RAB9ASIGMAR1KMT2ASMN1; SMN2 | |
| SCHEMBL8036049 | 0.84 | TMEM97 (0.52) | NPC1RAB9ATMEM97SIGMAR1ACKR3 | |
| SCHEMBL8788877 | 0.82 | NR1D1 (0.39) | NPC1CCR6PAX8ALDH1A1 | |
| SCHEMBL8053395 | 0.81 | SIGMAR1 (0.58) | NPC1RAB9ATMEM97SIGMAR1ACKR3 | |
| SCHEMBL8045372 | 0.80 | ACKR3 (0.43) | NPC1RAB9ATMEM97SIGMAR1ACKR3 | |
| SCHEMBL8787265 | 0.77 | CCR6 (0.42) | TMEM97SIGMAR1CCR6PAX8ALDH1A1 | |
| SCHEMBL8048207 | 0.77 | SIGMAR1 (0.45) | NPC1RAB9ATMEM97SIGMAR1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |