Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035979 | 0.88 | HSD17B10 (0.49) | DRD2DRD1DRD5DRD3MTNR1A | |
| SCHEMBL8039625 | 0.83 | AKR1B10 (0.46) | SLC6A4MTNR1ASMN1; SMN2HSD17B10MAPKAPK2 | |
| SCHEMBL11355122 | 0.76 | KDM4E (0.51) | DRD2DRD1DRD5DRD3MTNR1A | |
| SCHEMBL2707877 | 0.74 | MAPKAPK2 (0.62) | SMN1; SMN2MAPKAPK2MAPTBAZ2BALDH1A1 | |
| SCHEMBL11824158 | 0.73 | DRD2 (0.54) | DRD2DRD1DRD5DRD3SLC6A4 | |
| SCHEMBL6239283 | 0.72 | MAPKAPK2 (0.58) | DRD2DRD1DRD5DRD3SLC6A4 | |
| SCHEMBL15241465 | 0.72 | MAPT (0.55) | SMN1; SMN2MAPKAPK2MAPTMEN1KMT2A | |
| SCHEMBL7843326 | 0.72 | NOTUM (0.47) | DRD2DRD1DRD5DRD3MTNR1A | |
| SCHEMBL6234161 | 0.71 | MAPKAPK2 (0.59) | MTNR1ASMN1; SMN2MAPKAPK2MAPT | |
| SCHEMBL14363768 | 0.71 | SLC6A4 (0.48) | DRD2DRD1DRD5DRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |