Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035190 | 0.86 | POLB (0.39) | MEN1KMT2ACYP3A4ATG4B | |
| SCHEMBL8022533 | 0.84 | G6PD (0.38) | MEN1KMT2AG6PDCRHBPCRHR2 | |
| SCHEMBL8035129 | 0.84 | ALDH1A1 (0.39) | MEN1KMT2AHTR4PYGL | |
| SCHEMBL8028329 | 0.82 | G6PD (0.37) | MEN1KMT2ATDP1G6PDCRHBP | |
| SCHEMBL8038459 | 0.82 | TRPV1 (0.39) | G6PDCRHBPCRHR2 | |
| SCHEMBL8032230 | 0.80 | MAPT (0.38) | MEN1KMT2ATDP1G6PDCRHBP | |
| SCHEMBL3467921 | 0.78 | POLB (0.42) | MEN1KMT2ADRD2DRD3TP53 | |
| SCHEMBL8025556 | 0.75 | NPSR1 (0.42) | MEN1KMT2ATDP1G6PDCRHBP | |
| SCHEMBL8025557 | 0.73 | FAAH (0.36) | MEN1KMT2AG6PDCRHBPCRHR2 | |
| SCHEMBL8044942 | 0.71 | TDP1 (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |